2. Metabolic Enzyme/Protease
  3. Glucosidase
  4. 3-Oxo-hop-22(29)-ene

3-Oxo-hop-22(29)-ene 是一种 yeast α-glucosidase 抑制剂。3-Oxo-hop-22(29)-ene 具有中等的抗克氏锥虫和抗墨西哥利什曼原虫活性。3-Oxo-hop-22(29)-ene 具有微弱的抗炎活性。

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3-Oxo-hop-22(29)-ene Chemical Structure

3-Oxo-hop-22(29)-ene Chemical Structure

CAS No. : 25615-11-6

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3-Oxo-hop-22(29)-ene 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3-Oxo-hop-22(29)-ene is a yeast α-glucosidase inhibitor. 3-Oxo-hop-22(29)-ene shows a moderate effect on the viability of T. cruzi and L. mexicana. 3-Oxo-hop-22(29)-ene shows marginal activity of anti-inflammatory[1].

体外研究
(In Vitro)

3-Oxo-hop-22(29)-ene (compound 2) (50 μM; 24 hours) reduces the viability of T. cruzi by more than 20%, and has a moderate effecton on T. rangeli and L. mexicana[1].
3-Oxo-hop-22(29)-ene (10, 100 μM; 48 hours) causes 1.51% and 7.39% inhibition activity to yeast α-glucosidase respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

3-Oxo-hop-22(29)-ene 相关抗体:

Cell Viability Assay[1]

Cell Line: Saccharomyces cerevisiae (type 1) and mammalian yeast (type 2) α-glucosidases, T. cruzi, T. rangeli, L. mexicana
Concentration: 10 μM, 50 μM, 100 μM
Incubation Time: 24 hours, 48 hours
Result: Reduced the viability of T. cruzi by more than 20%, and had a moderate effecton on T. rangeli and L. mexicana
Inhibited Yeast α-glucosidase.
体内研究
(In Vivo)

3-Oxo-hop-22(29)-ene (0.31 μmol/ear; application; once) decreases 17.50 % the inflammation of mouse ear edema model[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult male CD-1 mice (25-30 g) (Mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA))[1]
Dosage: 0.31 μmol/ear
Administration: Apply to both faces of the right ear; once
Result: Decreased 17.50% the inflammation of mouse ear edema model.
分子量

424.70

Formula

C30H48O
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3-Oxo-hop-22(29)-ene 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Oxo-hop-22(29)-ene25615-11-6Glucosidaseanti-inflammationT. cruziT. rangeliL. mexicanaInhibitorinhibitorinhibit

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