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  4. 5-Methyl cromolyn disodium

5-Methyl cromolyn disodium  (Synonyms: C5OH)

目录号: HY-129085
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5-Methyl cromolyn (C5OH) disodium 是一种 Cromolyn (HY-B1619) 类似物，是一种 S100P 抑制剂。5-Methyl cromolyn disodium 可抑制 S100P 与其受体 RAGE 的结合、NF-κB 活性和细胞增殖，并促进 Gemcitabine (HY-17026) 诱导的细胞凋亡 (apoptosis)。5-Methyl cromolyn disodium 减少同基因 PDAC 小鼠模型中的肿瘤生长和转移并延长生存期。5-Methyl cromolyn disodium可用于胰腺癌 (如胰腺导管腺癌 (PDAC)) 研究。

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5-Methyl cromolyn disodium

5-Methyl cromolyn disodium Chemical Structure

CAS No. : 1221154-42-2

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5-Methyl cromolyn disodium 相关抗体

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生物活性

5-Methyl cromolyn (C5OH) disodium, an analog of Cromolyn (HY-B1619), is a S100P inhibitor. 5-Methyl cromolyn disodium inhibits the binding of S100P to its receptor RAGE, NF-κB activity and cell proliferation, and promotes Gemcitabine (HY-17026)-induced apoptosis. 5-Methyl cromolyn disodium reduces tumor growth and metastasis, and prolongs survival in mouse models of syngeneic PDAC. 5-Methyl cromolyn disodium can be used for pancreatic cancer like pancreatic ductal adenocarcinoma (PDAC) research[1].

分子量

540.38

Formula

C25H18Na2O11
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5-Methyl cromolyn disodium 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

5-Methyl cromolyn disodium1221154-42-2C5OHOthersCromolynInhibitorS100PNF-κBPancreatic cancerPancreatic ductal adenocarcinomaPDACMouse models of syngeneic PDACinhibitorinhibit

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