1. Protein Tyrosine Kinase/RTK
  2. PDGFR
  3. AG 1295

AG 1295 

目录号: HY-101957
产品使用指南

AG 1295 是一种选择性血小板衍生生长因子受体 (PDGFR) 酪氨酸激酶抑制剂。AG 1295 通过抑制 PDGFR-beta 引发的酪氨酸磷酸化,减少主动脉同种异体移植物血管病变的新内膜形成。

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AG 1295 Chemical Structure

AG 1295 Chemical Structure

CAS No. : 71897-07-9

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Description

AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG 1295 reduces neointimal formation in aortic allograft vasculopathy by inhibition of PDGFR-beta-triggered tyrosine phosphorylation[1][2].

IC50 & Target

PDGFR[1]

Molecular Weight

234.30

Formula

C₁₆H₁₄N₂

CAS No.

71897-07-9

SMILES

CC1=C(C)C=C2N=CC(C3=CC=CC=C3)=NC2=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
AG 1295
目录号:
HY-101957
需求量:

AG 1295

Cat. No.: HY-101957