2. Apoptosis
  3. TNF Receptor
  4. Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1)

Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) 

目录号: HY-P990269 纯度: 95.00%
COA 技术支持

Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) 是一种小鼠源性 IgG2a κ 型抗体抑制剂，靶向小鼠 CD40L/CD154。Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) 是原始 MR-1 抗体 (HY-P990134) 的嵌合版本。其可变区序列与原始 MR-1 相同，但恒定区序列已从亚美尼亚仓鼠 IgG 转换为小鼠 IgG2a。Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) 的 Fc 片段中含有 LALA-PG 突变，使其无法结合内源性 Fcγ 受体。Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) 可阻断 CD40/CD40L 信号通路。Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) 可用于癌症、炎症和免疫学研究。

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Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1)

Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) Chemical Structure

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规格 价格 是否有货 数量
500 μg ￥5600
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Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

生物活性

Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse CD40L/CD154. Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) is a chimeric version of the original MR-1 antibody (HY-P990134). The variable domain sequences are identical to the original MR-1 but the constant region sequences have been switched from Armenian hamster IgG to mouse IgG2a. Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) contains a LALA-PG mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) blocks CD40/CD40L signaling. Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) can be used for researches of cancer, inflammation and immunology.

同型

Mouse IgG2a (LALA-PG)
推荐同型对照抗体
反应种属

Mouse
IC50 & Target

CD40L/CD154 (LALA-PG)
基因 ID

21947  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 95.00%

COA (268 KB)

抗体抑制剂使用指南 (1152 KB)

Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1)TNF ReceptorTumor Necrosis Factor ReceptorTNFRCD40LCD154LALA-PGFcγ receptorsCancerInflammationImmunologyInhibitorinhibitorinhibit

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