2. 抗体
  3. Primary Antibodies
  4. SMAD7 抗体

SMAD7 抗体

目录号: HY-P81129
抗体使用指南

SMAD7 Antibody 是一个非偶联、分子量约 46 kDa、兔来源、抗 SMAD7 多克隆抗体。SMAD7 Antibody 可用于：人、小鼠、大鼠背景下 WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF 实验，且不带标记。

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规格 是否有货
50 μL   询价  
100 μL   询价  

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描述

SMAD7 Antibody is an unconjugated, approximately 46 kDa, rabbit-derived, anti-SMAD7 polyclonal antibody. SMAD7 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, and predicted: pig, cow background without labeling.
研究背景

转录调节因子（Transcriptin Regulators） Smad7是转化生长因子(TGF-β)信号通路的抑制分子，Smad7可干预MAPK信号通路,使ERK和JNK磷酸化活性的平衡失调,导致促增殖作用强于生长抑制作用,从而有助于细胞向恶性方向发展。
基因 ID

4092
中文名
Smad7抗体
同用名
MAD (mothers against decapentaplegic Drosophila) homolog 7; MAD; Mad homolog 7; MAD mothers against decapentaplegic homolog 7; MADH 7; MADH 8; MADH8; Mothers Against Decapentaplegic Drosophila Homolog of 7; Mothers against decapentaplegic homolog 7; Mothers against decapentaplegic homolog 8; Mothers against DPP homolog 7; Mothers against DPP homolog 8; SMA- AND MAD-RELATED PROTEIN 7; SMAD 7; SMAD; SMAD family member 7; SMAD, mothers against DPP homolog 7 (Drosophila); SMAD, mothers against DPP homolog 7; SMAD7_HUMAN.
分子量

Predicted band size: 46kDa
纯度

affinity purified
亚细胞定位

Nucleus. Cytoplasm. Note=Interaction with NEDD4L or RNF111 or induces translocation from the nucleus to the cytoplasm. TGF-beta stimulates its translocation from the nucleus to the cytoplasm. PDPK1 inhibits its translocation from the nucleus to the cytoplasm in response to TGF-beta.
偶联

Non-conjugated
产品类别

Primary Antibody; Rabbit Polyclonal Antibody
宿主

Rabbit
反应物种

Human, Mouse, Rat(predicted: Pig, Cow)
蛋白数据库

O15105
推荐稀释比例

WB: 1:500-2000;ELISA: 1:5000-10000;IHC-P: 1:100-500;IHC-F: 1:100-500;Flow-Cyt: 1ug/Test;ICC: 1:100;IF: 1:100-500

应用

WB; ELISA; IHC-P; IHC-F; Flow-Cyt; ICC; IF

性状

液体
组分

Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
运输条件

Shipping with blue ice.
同型

IgG
免疫原

KLH conjugated synthetic peptide derived from human Smad7: 1-100/426
文件资料
抗体使用指南 (1083 KB)
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号：
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