2. Biology Dictionary
  3. Phosphatidylinositol 3-kinase (PI3K)

Phosphatidylinositol 3-kinase (PI3K) 磷脂酰肌醇 3 激酶

释义：

Phosphatidylinositol 3-kinase (PI3K) is lipid kinases that regulate diverse cellular processes including proliferation, adhesion, survival, and motility. Dysregulated PI3K pathway signaling occurs in one-third of human tumors. Aberrantly activated PI3K signaling also confers sensitivity and resistance to conventional therapies. PI3K has been recognized as an attractive molecular target for novel anti-cancer molecules.

磷脂酰肌醇 3 激酶 (PI3Ks) 是调节多种细胞过程的脂质激酶，包括增殖、粘附、存活和运动。在三分之一的人类肿瘤中，PI3K 信号通路发生异常。异常激活的PI3K信号也会对传统疗法产生敏感性和耐药性。PI3K 被认为是一种具有吸引力的新型抗癌分子靶点。

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