1. Immunology/Inflammation Metabolic Enzyme/Protease
  2. Lipoxygenase COX
  3. COX-2/LOX-IN-2

COX-2/LOX-IN-2 (compound 6) 是 COX-2/LOX 的双抑制剂,IC50s 分别为 7.0 μM 和 27.5 μM。COX-2/LOX-IN-2 具有抗氧化活性,有潜力用于研制非甾体类抗炎药 (tNSAID)。

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COX-2/LOX-IN-2 Chemical Structure

COX-2/LOX-IN-2 Chemical Structure

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     可免费申领三个不同产品的试用装。

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

COX-2/LOX-IN-2 (compound 6) is a dual inhibitor of COX-2/LOX with IC50s of 7.0 μM and 27.5 μM, respectively. COX-2/LOX-IN-2 has antioxidant activity and has the potential to be used in the development of nonsteroidal anti-inflammatory drugs (tNSAIDs)[1].

IC50 & Target

7.0 μM (COX-2), 27.5 μM (Lipoxygenase, LOX)[1]

分子量

454.95

Formula

C28H23ClN2O2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
COX-2/LOX-IN-2
目录号:
HY-163188
需求量: