1. Metabolic Enzyme/Protease
  2. Ser/Thr Kinase Lipoxygenase
  3. CSBP ligand 1

CSBP ligand 1 (Compound 36) 是一种 CSBP 的配体,对 CSBP 结合的 IC50 为 0.08 μM。CSBP ligand 1 在 LPS (HY-D1056) 处理的小鼠中可抑制 TNF 的产生。CSBP ligand 1 对 PGHS-1 (IC50: 16 μM) 和 5-LO (IC50: 60 μM) 无显著的抑制活性。CSBP ligand 1 可用于炎症相关疾病的研究。

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CSBP ligand 1

CSBP ligand 1 Chemical Structure

CAS No. : 165806-32-6

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生物活性

CSBP ligand 1 (Compound 36) is a ligand of CSBP, with an IC50 of 0.08 μM for CSBP binding. CSBP ligand 1 can inhibit the production of TNF in mice treated with LPS (HY-D1056). CSBP ligand 1 has no significant inhibitory activity against PGHS-1 (IC50: 16 μM) and 5-LO (IC50: 60 μM). CSBP ligand 1 can be used in the research of inflammation-related diseases[1].

分子量

279.31

Formula

C17H14FN3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CSBP ligand 1
目录号:
HY-178214
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