2. Anti-infection Metabolic Enzyme/Protease
  3. Fungal Cytochrome P450
  4. CYP51-IN-27

CYP51-IN-27 是一种甾醇 14α-脱甲基酶 CYP51 抑制剂，其 IC50 值为 0.3434 μg/mL。CYP51-IN-27 具有抗真菌活性，能抑制真菌麦角甾醇的生成。CYP51-IN-27 可用于感染相关研究，如水稻纹枯病。

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CYP51-IN-27

CYP51-IN-27 Chemical Structure

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CYP51-IN-27 相关抗体

Top Publications Citing Use of Products

查看 Cytochrome P450 亚型特异性产品:

查看所有亚型
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CYP51-IN-27 is a sterol 14α-demethylase CYP51 inhibitor with an IC50 of 0.3434 μg/mL. CYP51-IN-27 exhibits antifungal activity and inhibits the production of fungal ergosterol. CYP51-IN-27 can be used for the research of infection, such as rice sheath blight[1].

IC50 & Target[1]

CYP51

0.3434 μg/mL (IC50)

体外研究
(In Vitro)

CYP51-IN-27 (Compound 4r) 对立枯丝核菌 (R. solani) 表现出优异的效力，其 EC50 值为 0.33 μg/mL[1]。
CYP51-IN-27 (20 μg/mL, 4 days) 会导致立枯丝核菌 (R. solani) 的菌丝体变得干燥、扭曲且形态不规则，表面粗糙、起皱并塌陷，还伴有一些碎片的产生[1]。
CYP51-IN-27 (200 μg/mL, 7-28 days) 对水稻植株上的立枯丝核菌 (R. solani) 表现出良好的保护和治疗活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CYP51-IN-27 相关抗体:
分子量

446.35

Formula

C22H12F6N4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CYP51-IN-27 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CYP51-IN-27FungalCytochrome P450CYPsantifungal activityCYP51Rhizoctonia solanirice plantsrice sheath blightergosterolInhibitorinhibitorinhibit

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目录号：
HY-178162
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