1. Cell Cycle/DNA Damage Antibody-drug Conjugate/ADC Related
  2. DNA Alkylator/Crosslinker ADC Cytotoxin
  3. DGN462

DGN462 是一种有效的 DNA 烷基化剂,具有抗肿瘤活性,如抗急性髓系白血病 (AML)。DGN462 可以作为 ADC 毒素分子合成 ADC。

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DGN462 Chemical Structure

DGN462 Chemical Structure

CAS No. : 1394079-41-4

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规格 是否有货
5 mg
询价
10 mg
询价

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML). DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs)[1].

体外研究
(In Vitro)

DGN462 is a member of the DNA-alkylating indolinobenzodiazepine pseudodimers (IGNs) class[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

942.13

Formula

C53H59N5O9S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
DGN462
目录号:
HY-101150
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