2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. ESP-31015

ESP-31015 (ETC-1001) 是一种口服有效的非贝特类 PPARα 激动剂。ESP-31015 在肥胖的 Zucker 大鼠模型中表现出显著的脂质调节作用。ESP-31015 可用于心血管疾病的研究。

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ESP-31015

ESP-31015 Chemical Structure

CAS No. : 413624-55-2

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ESP-31015 相关抗体

Top Publications Citing Use of Products

查看 PPAR 亚型特异性产品:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ESP-31015 (ETC-1001) is an orally active and non-fibrate based PPARα agonists. ESP-31015 demonstrates significant lipid-regulating effects in the obese Zucker rat model. ESP-31015 can be used in cardiovascular disease research[1].

IC50 & Target[1]

PPARα

 

体内研究
(In Vivo)

ESP-31015 (100 mg/kg，口服，每日一次，持续 2 周) 在脂肪大鼠中可使血清高密度脂蛋白胆固醇 (HDL-C) 水平升高 34.6%，血清甘油三酯水平降低 71%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female obese Zucker fatty rats model[1]
Dosage: 100 mg/kg
Administration: Oral administration (p.o.), once daily for 2 weeks
Result: Showed a 34.6% increase in serum HDL-cholesterol and a 71% reduction in serum triglycerides.
分子量

286.45

Formula

C17H34O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ESP-31015 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ESP-31015413624-55-2ETC-1001ESP31015ESP 31015ETC1001ETC 1001PPARPeroxisome proliferator-activated receptorsHDL elevatorsHDL mimeticsreverse cholesterol transport (RCT)PPARα agonistsCETP inhibitorsApoA-I mimeticsatherosclerosis therapeuticsdyslipidemia treatmentInhibitorinhibitorinhibit

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产品名称：
ESP-31015
目录号：
HY-107054
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