2. Anti-infection Metabolic Enzyme/Protease
  3. Parasite Cathepsin SARS-CoV
  4. Gallinamide A TFA

Gallinamide A TFA 

目录号: HY-N10109A 纯度: 99.85%
COA 产品使用指南

摩尔计算器

Gallinamide A TFA 是一种线性沉积肽，是组织蛋白酶 L (CatL) 的有效抑制剂 (IC50: 17.6 pM)。Gallinamide A TFA 通过抑制 CatL 来抑制 SARS-CoV-2 感染 (EC50: 28 nM)。Gallinamide A TFA 还抑制恶性疟原虫 (IC50: 50 nM)。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Gallinamide A TFA Chemical Structure

Gallinamide A TFA Chemical Structure

CAS No. : 1352920-57-0

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥5330
In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Gallinamide A TFA:

Gallinamide A TFA 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

查看所有亚型
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

查看 Cathepsin 亚型特异性产品:

查看所有亚型
Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gallinamide A TFA is a linearly depositing peptide and a potent inhibitor of cathepsin L (CatL) (IC50: 17.6 pM). Gallinamide A TFA inhibits SARS-CoV-2 infection by inhibiting CatL (EC50: 28 nM). Gallinamide A TFA also inhibits Plasmodium falciparum (IC50: 50 nM)[1][2].

IC50 & Target

IC50: 17.6 pM (Cathepsin L); 7.34 nM (Cathepsin B); 697 nM (Cathepsin V); 79.6 nM (Cathepsin K); 367 pM (Cathepsin S)[1]
EC50: 28 nM (SARS-CoV-2)[1]
IC50: 50 nM (P. falciparum)[2]
体外研究
(In Vitro)

Gallinamide A TFA 对细胞毒性低，对 VeroE6 细胞的 CC50 >100 μM。Gallinamide A TFA (0.5 μM; 96 h) 可以通过抑制 CatL 介导的 SARS-CoV-2 内体进入 VeroE6 细胞[1].
Gallinamide A TFA 还与 TMPRSS2 抑制剂 Nafamostat mesylate (HY-B0190A) 表现出协同作用。在 HEK-ACE2-TMPRSS2 细胞中具有有效的抗病毒活性，但在 VeroE6 细胞系中无效[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Gallinamide A TFA 相关抗体:
分子量

706.79

Formula

C33H53F3N4O9
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源

marine cyanobacterium Schizothrix sp.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料
参考文献

Gallinamide A TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gallinamide A1352920-57-0ParasiteCathepsinSARS-CoVSARS coronavirusInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Gallinamide A TFA
目录号：
HY-N10109A
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z