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  2. Map3k8 - mitogen-activated protein kinase kinase kinase 8 Gene

Map3k8 - mitogen-activated protein kinase kinase kinase 8 Gene

中文名称:丝裂原活化蛋白激酶激酶激酶 8

种属: Rattus norvegicus

同用名: Tpl2; Tpl-2; D17TPL2

基因 ID: 116596 | 基因类型: protein coding

关于 Map3k8

Primary_assembly 17: 53,383,131-53,403,216 forward strand.mRatBN7.2:CM026990.1

This gene has 2 transcripts (splice variants), 199 orthologues, 36 paralogues and is associated with 23 phenotypes. Biased expression in Spleen (RPKM 18.2), Lung (RPKM 65.) and 8 other tissues.

功能概要

该基因编码的蛋白可启动 MAP 激酶激酶激酶活性。预计参与MAPK级联;免疫系统过程;和蛋白质磷酸化。预测位于胞质溶胶中。与人 MAP3K8(丝裂原活化蛋白激酶激酶 8)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables MAP kinase kinase kinase activity. Predicted to be involved in MAPK cascade; immune system process; and protein phosphorylation. Predicted to be located in cytosol. Orthologous to human MAP3K8 (mitogen-activated protein kinase kinase kinase 8). [provided by Alliance of Genome Resources, Apr 2022]

Map3k8 基因产物(1)

mRNA Protein Name
NM_053847.2 NP_446299.2 mitogen-activated protein kinase kinase kinase 8

Map3k8 蛋白结构

STKc_MAP3K8

STKc_MAP3K8: cd13995 (132 - 387)

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  • 467 a.a.
蛋白主名 其他名称

mitogen-activated protein kinase kinase kinase 8

serine/threonine kinase (Tpl-2)

tumor progression locus 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map3k8 NCBI NCBI:1326