2. Gene
  3. MEI1 - meiotic double-stranded break formation protein 1 Gene

MEI1 - meiotic double-stranded break formation protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：减数分裂双链断裂形成蛋白 1

种属: Homo sapiens

同用名: HYDM3; SPATA38

基因 ID: 150365 | 基因类型: protein coding

关于 MEI1

Cytogenetic location: 22q13.2 Genomic coordinates (GRCh38): 22:41,699,503-41,799,454 (from NCBI)

This gene has 16 transcripts (splice variants), 181 orthologues, 2 paralogues and is associated with 2 phenotypes. Biased expression in testis (RPKM 5.5), spleen (RPKM 2.0) and 13 other tissues.

功能概要

预计参与减数分裂 I。预计在配子世代的上游或内部发挥作用；减数分裂纺锤体组织；和减数分裂端粒聚集。涉及妊娠滋养细胞肿瘤。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in meiosis I. Predicted to act upstream of or within gamete generation; meiotic spindle organization; and meiotic telomere clustering. Implicated in gestational trophoblastic neoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MEI1 基因产物(1)

mRNA Protein Name
NM_152513.4 NP_689726.3 meiosis inhibitor protein 1
蛋白主名 其他名称

meiosis inhibitor protein 1

meiosis defective 1

关联疾病

疾病名称 别名
Hydatidiform Mole, Recurrent, 3

HYDM3
Hydatidiform Mole, Recurrent, 1

Hydatidiform Mole

Gestational Trophoblastic Disease

Complete Hydatidiform Mole

Hydm

HYDM1

Chm

Molar Pregnancy

Hydatidiform Mole, Complete

Hydatid Mole

Complete Molar Pregnancy

Mole, Hydatidiform, Recurrent, Type 1

Gestational Trophoblastic Neoplasms

Hydatidiform Mole, Recurrent, 2

Classical Hydatidiform Mole
Trophoblastic Neoplasm

Trophoblastic Tumor

Trophoblastic Neoplasms
Gestational Trophoblastic Neoplasm

Hydatidiform Mole

Molar Pregnancy

Gestational Trophoblastic Neoplasia

Gestational Trophoblastic Tumor

Gtn

Gestational Trophoblastic Disease

Gestational Trophoblastic Neoplasms

Hydatidiform Mole, Recurrent, 1

Hydatidiform Mole Benign

Trophoblastic Disease

Trophoblastic Disease Nos

Trophoblastic Disorder

Vesicular Mole Nos

Vesicular Mole

Hydatidiform Mole Nos
Lumbosacral Lipoma
Spermatogenic Failure 5

Male Infertility With Large-Headed, Multiflagellar, Polyploid Spermatozoa

Infertility Associated With Multi-Tailed Spermatozoa And Excessive Dna

SPGF5

Macrocephalic Sperm Head Syndrome

Male Infertility Due To Macrozoospermia

Infertility Associated With Multitailed Spermatozoa And Excessive Dna

Macrozoospermia

Male Infertility Due To Large-Headed Multiflagellar Polyploid Spermatozoa

Infertility Associated With Multi-Tailed Spermatozoa And Excessive Deoxyribonucleic Acid

Large-Headed Multiflagellar Polyploid Spermatozoa

Male Infertility With Large-Headed Multiflagellar Polyploid Spermatozoa
Cerebrooculofacioskeletal Syndrome 2

COFS2

Cerebro-Oculo-Facio-Skeletal Syndrome 2

Cofs Syndrome
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-132870 MEIS-IN-2 Inhibitor / 否
HY-155526 FY-21 Inhibitor / 否
HY-160018 BAY-155 Inhibitor / 否
HY-RS08319 MEI1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS08325 MEIS1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus MEI1 MGD MGI:3028590
Bos taurus MEI1 VGNC VGNC:31378
Felis catus MEI1 VGNC VGNC:63446
Canis familiaris MEI1 VGNC VGNC:43149
Macaca mulatta MEI1 VGNC VGNC:95361
Rattus norvegicus MEI1 RGD RGD:1307210
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