Mapkapk2 - MAP kinase-activated protein kinase 2 Gene

中文名称：MAP 激酶活化蛋白激酶 2

种属: Mus musculus

同用名: MK2; MK-2; Rps6kc1; MAPKAP-K2

关于 Mapkapk2

功能概要

该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性。涉及多个过程，包括巨胞饮作用；调节细胞因子的产生；和对脂多糖的反应。作用于内耳发育的上游或内耳发育； p38MAPK 级联；和基因表达的正调控。位于细胞质和细胞核中。以多种结构表达，包括中枢神经系统；眼睛;泌尿生殖系统；直觉;和免疫系统。与人 MAPKAPK2（MAPK 活化蛋白激酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein serine/threonine kinase activity. Involved in several processes, including macropinocytosis; regulation of cytokine production; and response to lipopolysaccharide. Acts upstream of or within inner ear development; p38MAPK cascade; and positive regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and immune system. Orthologous to human MAPKAPK2 (MAPK activated protein kinase 2). [provided by Alliance of Genome Resources, Apr 2022]