2. Gene
  3. Npy2r - neuropeptide Y receptor Y2 Gene

Npy2r - neuropeptide Y receptor Y2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：神经肽 Y 受体 Y2

种属: Mus musculus

同用名: NPY2-R

基因 ID: 18167 | 基因类型: protein coding

关于 Npy2r

Chromosome 3: 82,445,690-82,455,391 reverse strand.GRCm39:CM000996.3

This gene has 4 transcripts (splice variants), 248 orthologues, 55 paralogues and is associated with 40 phenotypes. Biased expression in adrenal adult (RPKM 1.5), genital fat pad adult (RPKM 1.1) and 11 other tissues.

功能概要

该基因编码的蛋白可启动肽 YY 受体活性。作用于腺苷酸环化酶抑制 G 蛋白偶联受体信号通路的上游或内部。位于非运动纤毛中。在中枢神经系统中表达；背根神经节；眼睛;和后肾。该基因的人类直系同源物与亨廷顿病有关；病态肥胖;和肥胖。与人 NPY2R（神经肽 Y 受体 Y2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables peptide YY receptor activity. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Located in non-motile cilium. Is expressed in central nervous system; dorsal root ganglion; eye; and metanephros. Human ortholog(s) of this gene implicated in Huntington's disease; morbid obesity; and obesity. Orthologous to human NPY2R (Neuropeptide Y Receptor Y2). [provided by Alliance of Genome Resources, Apr 2022]

Npy2r 基因产物(5)

mRNA Protein Name
NM_001410444.1 NP_001397373.1 neuropeptide Y receptor type 2 isoform 1
NM_001410445.1 NP_001397374.1 neuropeptide Y receptor type 2 isoform 1
NM_008731.4 NP_032757.2 neuropeptide Y receptor type 2 isoform 1
NM_001205099.2 NP_001192028.1 neuropeptide Y receptor type 2 isoform 2
NM_001410443.1 NP_001397372.1 neuropeptide Y receptor type 2 isoform 1

Npy2r 蛋白结构

7tmA_NPY2R

7tmA_NPY2R: cd15399 (50 - 335)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (51 - 77)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (84 - 109)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (122 - 152)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (163 - 184)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (215 - 244)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (260 - 290)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (303 - 328)

  • 0
  • 100
  • 200
  • 300
  • 381 a.a.
蛋白主名 其他名称

neuropeptide Y receptor type 2

NPY-Y2 receptor

Y2 receptor

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101986A BIIE-0246 hydrochloride Antagonist ≥99.0% 否
HY-RS09514 NPY2R Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09515 Npy2r Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09516 NPY2R Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Npy2r NCBI NCBI:4887
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