1. Gene
  2. Ntsr1 - neurotensin receptor 1 Gene

Ntsr1 - neurotensin receptor 1 Gene

中文名称:神经降压素受体 1

种属: Mus musculus

同用名: NTR1; NT-1R; NTR-1

基因 ID: 18216 | 基因类型: protein coding

关于 Ntsr1

Chromosome 2: 180,141,769-180,186,773 forward strand.GRCm39:CM000995.3

This gene has 2 transcripts (splice variants), 213 orthologues, 14 paralogues and is associated with 16 phenotypes. Biased expression in CNS E18 (RPKM 4.6), genital fat pad adult (RPKM 1.5) and 1 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动 G 蛋白偶联神经降压素受体活性;相同的蛋白质结合活性;和蛋白质 N 末端结合活性。在成人运动行为的上游或内部起作用。预计位于多个细胞成分中,包括树突;核周;和对称突触。预计是质膜的组成部分。预计在质膜上有活性。以多种结构表达,包括中枢神经系统;眼睛;胆囊;肠;和雄性生殖腺或器官。该基因的人类直系同源物与精神分裂症有关。与人类 NTSR1(神经降压素受体 1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled Neurotensin Receptor activity; identical protein binding activity; and protein N-terminus binding activity. Acts upstream of or within adult locomotory behavior. Predicted to be located in several cellular components, including dendrite; perikaryon; and symmetric synapse. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; eye; gallbladder; intestine; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human NTSR1 (Neurotensin Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ntsr1 基因产物(1)

mRNA Protein Name
NM_018766.2 NP_061236.1 neurotensin receptor type 1

Ntsr1 蛋白结构

7tmA_NTSR1

7tmA_NTSR1: cd15355 (63 - 90)

7tmA_NTSR1

7tmA_NTSR1: cd15355 (63 - 379)

7tmA_NTSR1

7tmA_NTSR1: cd15355 (100 - 126)

7tmA_NTSR1

7tmA_NTSR1: cd15355 (140 - 170)

7tmA_NTSR1

7tmA_NTSR1: cd15355 (182 - 204)

7tmA_NTSR1

7tmA_NTSR1: cd15355 (232 - 261)

7tmA_NTSR1

7tmA_NTSR1: cd15355 (300 - 330)

7tmA_NTSR1

7tmA_NTSR1: cd15355 (347 - 372)

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  • 424 a.a.
蛋白主名 其他名称

neurotensin receptor type 1

NT-R-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ntsr1 NCBI NCBI:4923
Macaca fascicularis Ntsr1 NCBI NCBI:102115340