1. Gene
  2. Rel - reticuloendotheliosis oncogene Gene

Rel - reticuloendotheliosis oncogene Gene


种属: Mus musculus

同用名: c-Rel

基因 ID: 19696 | 基因类型: protein coding

关于 Rel

Chromosome 11: 23,686,847-23,720,970 reverse strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 208 orthologues, 4 paralogues and is associated with 72 phenotypes. Broad expression in spleen adult (RPKM 6.1), thymus adult (RPKM 3.) and 21 other tissues.


该基因编码的蛋白可启动 DNA 结合转录因子活性。在白细胞介素 12 产生的正调控和转录的正调控、DNA 模板的上游或内部起作用。位于细胞质和细胞核中。用眼睛表达;泌尿生殖系统;和心。与人类 REL(REL 原癌基因,NF-kB 亚基)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables DNA-binding transcription factor activity. Acts upstream of or within positive regulation of interleukin-12 production and positive regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. Is expressed in eye; genitourinary system; and heart. Orthologous to human REL (REL proto-oncogene, NF-kB subunit). [provided by Alliance of Genome Resources, Apr 2022]

Rel 基因产物(1)

mRNA Protein Name
NM_009044.3 NP_033070.2 proto-oncogene c-Rel

Rel 蛋白结构


RHD-n_c-Rel: cd07933 (7 - 178)


IPT_NFkappaB: cd01177 (185 - 280)

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  • 588 a.a.
蛋白主名 其他名称

proto-oncogene c-Rel

C-Rel proto-oncogene protein


种属 基因名 来源 基因 ID
Homo sapiens Rel NCBI NCBI:5966
Canis familiaris Rel NCBI NCBI:474606
Macaca fascicularis Rel NCBI NCBI:102116653
Canis lupus familiaris Rel NCBI
Rattus norvegicus Rel NCBI NCBI:305584
Macaca mulatta Rel NCBI NCBI:717804