2. Gene
  3. Rel - reticuloendotheliosis oncogene Gene

Rel - reticuloendotheliosis oncogene Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：网状内皮增生癌基因

种属: Mus musculus

同用名: c-Rel

基因 ID: 19696 | 基因类型: protein coding

关于 Rel

Chromosome 11: 23,686,847-23,720,970 reverse strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 208 orthologues, 4 paralogues and is associated with 72 phenotypes. Broad expression in spleen adult (RPKM 6.1), thymus adult (RPKM 3.) and 21 other tissues.

功能概要

该基因编码的蛋白可启动 DNA 结合转录因子活性。在白细胞介素 12 产生的正调控和转录的正调控、DNA 模板的上游或内部起作用。位于细胞质和细胞核中。用眼睛表达；泌尿生殖系统；和心。与人类 REL（REL 原癌基因，NF-kB 亚基）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA-binding transcription factor activity. Acts upstream of or within positive regulation of interleukin-12 production and positive regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. Is expressed in eye; genitourinary system; and heart. Orthologous to human REL (REL proto-oncogene, NF-kB subunit). [provided by Alliance of Genome Resources, Apr 2022]

Rel 基因产物(1)

mRNA Protein Name
NM_009044.3 NP_033070.2 proto-oncogene c-Rel

Rel 蛋白结构

RHD-n_c-Rel

RHD-n_c-Rel: cd07933 (7 - 178)

IPT_NFkappaB

IPT_NFkappaB: cd01177 (185 - 280)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 588 a.a.
蛋白主名 其他名称

proto-oncogene c-Rel

C-Rel proto-oncogene protein

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-17371A (rel)-Oxaliplatin / 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-122359A rel-Levormeloxifene / Phase 3
Pre-clinical Phase
生物活性分子 (72)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15917 DL-dithiothreitol 99.43% 否
HY-12276 MALT1 inhibitor MI-2 Inhibitor 99.95% 否
HY-139426A (rel)-ML-SI3 99.81% 否
HY-119940 MC180295 Inhibitor 98.89% 否
HY-124179 IT-901 Inhibitor ≥99.0% 否
HY-121508 (E/Z)-IT-603 Inhibitor 99.91% 否
HY-120006A (rel)-AR234960 Agonist 99.42% 否
HY-112163A rel-Zotatifin 97.32% 否
HY-B1890 (±)-Catechin Inhibitor 98.38% 否
HY-N0683A rel-α-Vitamin E ≥70.0% 否
HY-160440 rel-VU6021625 99.00% 否
HY-113068 (rel)-β-Tocopherol Inhibitor ≥99.0% 否
HY-160477 DC-SX029 Inhibitor 98.07% 否
HY-128838A (rel)-PROTAC ERRα Degrader-1 95.89% 否
HY-114324A rel-PROTAC PARP1 degrader Degrader / 否
HY-121964 cis-Piperidine-2,3-dicarboxylic acid Agonist ≥98.0% 否
HY-18941B (rel)-Eglumegad Agonist ≥97.0% 否
HY-77493 (rel)-Tivantinib 96.45% 否
HY-N2207 rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan 99.95% 否
HY-101387 rel-ACPT-I Agonist / 否
HY-158820 Cosdosiran / 否
HY-158820A Cosdosiran sodium / 否
HY-110020 rel-O-2050 Antagonist / 否
HY-122495 rel-Quinpirole dihydrochloride Agonist / 否
HY-12422C rel-(2S,3R)-Voruciclib Inhibitor / 否
HY-124874 (rel)-Asperparaline A Antagonist / 否
HY-13204S1 rel-Biperiden-d5 Inhibitor / 否
HY-13204S2 rel-Biperiden EP impurity A-d5 Inhibitor / 否
HY-13204S3 rel-Biperiden EP impurity B-d5 Inhibitor / 否
HY-13607A (rel)-BMS-641988 Antagonist / 否
HY-140902 rel-Biotin-PEG3-C3-NH2 / 否
HY-143785S rel-Saxagliptin-15N,d2 hydrochloride / 否
HY-144681A rel-(2R,4R)-LY3372689 Inhibitor / 否
HY-14588S (rel)-Lopinavir-d8 / 否
HY-14645B DHMEQ racemate Inhibitor / 否
HY-151216S rel-Paroxetine-d4 hydrochloride / 否
HY-15793A Trans (2,3)-Dihydrotetrabenazine Inhibitor / 否
HY-17423S1 rel-Abacavir-d4 / 否
HY-17447SA Tranylcypromine-d5 hydrochloride Inhibitor / 否
HY-18295A rel-Erteberel Agonist / 否
HY-18617 rel-SB-612111 hydrochloride Inhibitor / 否
HY-65039A rel-Boc-Hyp-OMe / 否
HY-78746A (3S,4R,5S)-rel-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxylic acid 96.90% 否
HY-90001S3 rel-Ritonavir-d6 ≥98.0% 否
HY-B0141S7 rel-Estradiol-13C6 / 否
HY-B0176AS rel-Sertraline-d3 hydrochloride Inhibitor / 否
HY-B0511S1 rel-Biotin-d4 98.04% 否
HY-E70364 IgdE protease / 否
HY-N10837 rel-3R-Methoxy-4S-furanogermacra-1E,10(15)-dien-6-one / 否
HY-RS06707 IL17REL Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11823 REL Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11824 Rel Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11825 Rel Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W015597S rel-3a,4,7,7a-Tetrahydro-1H-isoindole-1,3(2H)-dione-d6 / 否
HY-W588220 rel-cis-Pinic acid / 否
HY-W745349 rel-(1S,2R)-Dihydro bupropion-d9 hydrochloride / 否
HY-W756041 rel-(1S,2S)-Dihydro bupropion-d9 hydrochloride / 否
HY-100243A Norcisapride / 否
HY-10285S1 (rel)-Saxagliptin-13C,d2 TFA Inhibitor / 否
HY-113239S1 rel-Hydroxycotinine-d3 / 否
HY-12422E rel-(2S,3R)-Voruciclib hydrochloride / 否
HY-128732 rel-(2R,3S)-2,3-Dihydroxysuccinic acid hydrate / 否
HY-13047A rel-S-(+)-Mecamylamine hydrochloride / 否
HY-134180 rel-Carbovir monophosphate / 否
HY-138110 Toladryl Antagonist / 否
HY-14690B rel-Ecopipam hydrobromide Antagonist / 否
HY-157571S N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8 / 否
HY-157856 rel-4(5)-Epdpe methyl ester / 否
HY-18957A rel-Lifirafenib / 否
HY-B0492S rel-Paroxetine-d4-1 hydrochloride / 否
HY-W710914A rel-HDMP 28 hydrochloride / 否
HY-W777138 rel-(1S,2R)-Dihydro bupropion-d9 / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rel NCBI NCBI:5966
Canis familiaris Rel NCBI NCBI:474606
Macaca fascicularis Rel NCBI NCBI:102116653
Canis lupus familiaris Rel NCBI
Rattus norvegicus Rel NCBI NCBI:305584
Macaca mulatta Rel NCBI NCBI:717804
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