2. Gene
  3. OARD1 - O-acyl-ADP-ribose deacylase 1 Gene

OARD1 - O-acyl-ADP-ribose deacylase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：O-酰基-ADP-核糖脱酰酶 1

种属: Homo sapiens

同用名: TARG1; C6orf130; dJ34B21.3

基因 ID: 221443 | 基因类型: protein coding

关于 OARD1

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:41,064,772-41,097,787 (from NCBI)

This gene has 16 transcripts (splice variants) and 240 orthologues. Ubiquitous expression in testis (RPKM 36.5), thyroid (RPKM 20.0) and 25 other tissues.

功能概要

该基因编码的蛋白质是一种脱酰酶，可将 O-乙酰基-ADP-核糖转化为 ADP-核糖和乙酸，将 O-丙酰基-ADP-核糖转化为 ADP-核糖和丙酸，将 O-丁酰基-ADP-核糖转化为 ADP -核糖和丁酸盐。 ADP-核糖产物能够通过竞争性反馈回路抑制这些反应。[RefSeq 提供，2016 年 7 月]

The protein encoded by this gene is a deacylase that can convert O-acetyl-ADP-ribose to ADP-ribose and acetate, O-propionyl-ADP-ribose to ADP-ribose and propionate, and O-butyryl-ADP-ribose to ADP-ribose and butyrate. The ADP-ribose product is able to inhibit these reactions through a competitive feedback loop. [provided by RefSeq, Jul 2016]

OARD1 基因产物(13)

mRNA Protein Name
NM_001329684.2 NP_001316613.1 ADP-ribose glycohydrolase OARD1 isoform a
NM_001329685.1 NP_001316614.1 ADP-ribose glycohydrolase OARD1 isoform a
NM_001329686.2 NP_001316615.1 ADP-ribose glycohydrolase OARD1 isoform a
NM_001329688.2 NP_001316617.1 ADP-ribose glycohydrolase OARD1 isoform a
NM_001329689.2 NP_001316618.1 ADP-ribose glycohydrolase OARD1 isoform b
NM_001329690.2 NP_001316619.1 ADP-ribose glycohydrolase OARD1 isoform c
NM_001329691.2 NP_001316620.1 ADP-ribose glycohydrolase OARD1 isoform c
NM_001329692.1 NP_001316621.1 ADP-ribose glycohydrolase OARD1 isoform c
NM_001329693.2 NP_001316622.1 ADP-ribose glycohydrolase OARD1 isoform c
NM_001329694.2 NP_001316623.1 ADP-ribose glycohydrolase OARD1 isoform d
NM_001329695.1 NP_001316624.1 ADP-ribose glycohydrolase OARD1 isoform d
NM_001329696.2 NP_001316625.1 ADP-ribose glycohydrolase OARD1 isoform d
NM_145063.4 NP_659500.1 ADP-ribose glycohydrolase OARD1 isoform a

OARD1 蛋白结构

Macro

Macro: Macro domain (35 - 134)

  • 0
  • 100
  • 152 a.a.
蛋白主名 其他名称

ADP-ribose glycohydrolase OARD1

O-acetyl-ADP-ribose deacetylase 1

重组 OARD1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71658 OARD1 Protein, Human (Myc, His) Q9Y530 (2A-152L) ≥95%

关联疾病

疾病名称 别名
Arthrogryposis, Renal Dysfunction, And Cholestasis 1

Arc Syndrome

ARCS1

Arthrogryposis Renal Dysfunction Cholestasis Syndrome

Arthrogryposis-Renal Dysfunction-Cholestasis Syndrome

Arcs

Arthrogryposis, Renal Dysfunction And Cholestasis Syndrome

Arthrogryposis, Renal Dysfunction, And Cholestasis

Arthrogryposis-Renal Dysfunction-Cholestasis

Arthrogryposis - Renal Dysfunction - Cholestasis

Arthrogryposis Multiplex Congenita, Renal Dysfunction, And Cholestasis

Arthrogryposis, Renal Dysfunction And Cholestasis Syndrome 1

Arthrogryposis Renal Dysfunction And Cholestasis 1

Arthrogryposis With Renal Dysfunction And Cholestasis Syndrome

Arthrogryposis, Renal Dysfunction, Cholestasis, Type 1

Kidney Failure

Renal Insufficiency
Brachydactyly, Type A4

Brachymesophalangy Ii And V

Temtamy Type Brachydactyly

Brachydactyly Type A4

BDA4

Brachymesophalangy 2 And 5

Brachydactyly Temtamy Type

Brachydactyly, Temtamy Type
Eastern Equine Encephalitis

Eee

Neuroinvasive Eastern Equine Encephalitis Virus Infection

Eastern Equine Encephalomyelitis

Encephalomyelitis, Eastern Equine

Triple E

Eastern Equine Encephalitis Virus Infection

Neuroinvasive Eastern Equine Encephalitis Virus Disease

Eee - [Eastern Equine Encephalitis]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09726 OARD1 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus OARD1 VGNC VGNC:32390
Felis catus OARD1 VGNC VGNC:102477
Canis familiaris OARD1 VGNC VGNC:44085
Mus musculus OARD1 MGD MGI:2146818
Rattus norvegicus OARD1 RGD RGD:1308299
Macaca mulatta OARD1 VGNC VGNC:75444
Others OARD1 NCBI
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