Smyd2 - SET and MYND domain containing 2 Gene

中文名称：含 SET 和 MYND 域 2

种属: Mus musculus

同用名: KMT3C; Zmynd14; 4930402C15; 1110020E07Rik

关于 Smyd2

功能概要

该基因编码的蛋白可启动 RNA 聚合酶 II 复合物结合活性和组蛋白甲基转移酶活性（H3-K36 特异性）。参与细胞群增殖和肽基-赖氨酸二甲基化的负调节。作用于组蛋白甲基化的上游或内部。位于细胞质和细胞核中。以多种结构表达，包括心脏；淋巴系统腺体；鼻腔上皮；神经系统;和视网膜。与人类 SMYD2 同源（SET 和 MYND 结构域包含 2）。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA polymerase II complex binding activity and Histone Methyltransferase activity (H3-K36 specific). Involved in negative regulation of cell population proliferation and peptidyl-lysine dimethylation. Acts upstream of or within histone methylation. Located in cytosol and nucleus. Is expressed in several structures, including heart; hemolymphoid system gland; nasal cavity epithelium; nervous system; and retina. Orthologous to human SMYD2 (SET and MYND domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]