2. Gene
  3. MOB4 - MOB family member 4, phocein Gene

MOB4 - MOB family member 4, phocein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：MOB 家族成员 4，phocein

种属: Homo sapiens

同用名: 2C4D; MOB1; MOB3; PHOCN; PREI3; CGI-95; MOBKL3

基因 ID: 25843 | 基因类型: protein coding

关于 MOB4

Cytogenetic location: 2q33.1 Genomic coordinates (GRCh38): 2:197,515,554-197,553,699 (from NCBI)

This gene has 8 transcripts (splice variants), 234 orthologues and 6 paralogues. Ubiquitous expression in adrenal (RPKM 20.9), esophagus (RPKM 14.5) and 25 other tissues.

功能概要

该基因是根据其与小鼠对应物的相似性来识别的。对小鼠对应物的研究表明，该基因的表达可能在合子基因激活后的卵母细胞成熟和植入前过程中受到调节。已经观察到编码不同亚型的可变剪接转录物变体。自然发生的通读转录发生在该基因座和相邻基因座 HSPE1 之间。[RefSeq 提供，2011 年 2 月]

This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011]

MOB4 基因产物(4)

mRNA Protein Name
NM_001100819.3 NP_001094289.1 MOB-like protein phocein isoform 3
NM_001204094.1 NP_001191023.1 MOB-like protein phocein isoform 2
NM_015387.5 NP_056202.2 MOB-like protein phocein isoform 1
NM_199482.4 NP_955776.1 MOB-like protein phocein isoform 2

MOB4 蛋白结构

Mob1_phocein

Mob1_phocein: Mob1/phocein family (40 - 208)

  • 0
  • 100
  • 200
  • 225 a.a.
蛋白主名 其他名称

MOB-like protein phocein

MOB1, Mps One Binder kinase activator-like 3

重组 MOB4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70940 MOB4 Protein, Human (His) Q9Y3A3 (M1-A225) ≥95%

关联疾病

疾病名称 别名
Cerebral Cavernous Malformations 3

Cerebral Cavernous Malformation 3

CCM3

Cerebral Cavernous Malformations-3

Cavernous Angiomatous Malformations

Cavernous Hemangioma Of The Brain

Cerebral Capillary Malformations

Cerebral Cavernoma

Familial Cavernous Angioma

Cerebral Cavernous Malformations, Type 3
Osteogenesis Imperfecta, Type X

Osteogenesis Imperfecta Type 10

OI10

Osteogenesis Imperfecta Type X

Oi, Type X

Osteogenesis Imperfecta 10

Oi Type X

Oi-X
Cerebral Cavernous Malformations

Cerebral Cavernous Malformation

Cavernous Malformations Of Cns And Retina

Cerebral Cavernous Malformation 1

Cavernous Angiomatous Malformations

Cerebral Capillary Malformations

CCM

Hyperkeratotic Cutaneous Capillary-Venous Malformations Associated With Cerebral Capillary Malformations

Familial Cavernous Angioma

Cavernous Angioma

Familial Cerebral Cavernous Malformation

Cerebral Cavernous Malformations 1

Cavernous Angioma, Familial

Cam

Cerebral Cavernous Malformations-1

Cavernoma

Central Nervous System Cavernous Hemangioma

Cerebral Cavernous Hemangioma

Familial Cavernous Hemangioma

Familial Cavernous Malformation

Familial Cerebral Cavernous Angioma

Intracerebral Cavernous Hemangioma

CCM1

Cavernous Hemangioma Of The Brain

Cerebral Cavernoma

Cerebral Cavernous Malformations, Type 1

Hemangioma, Cavernous, Central Nervous System

Hemangioma, Cavernous

Angioma, Cavernous
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08577 MOB4 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MOB4 RGD RGD:620183
Mus musculus MOB4 MGD MGI:104899
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