MMP10 - matrix metallopeptidase 10 Gene

中文名称：基质金属肽酶 10

种属: Homo sapiens

同用名: SL-2; STMY2

基因 ID: 4319 | 基因类型: protein coding

关于 MMP10

Cytogenetic location: 11q22.2 Genomic coordinates (GRCh38): 11:102,770,502-102,780,628 (from NCBI)

This gene has 2 transcripts (splice variants), 516 orthologues and 23 paralogues. Restricted expression toward endometrium (RPKM 266.6).

功能概要

该基因编码基质金属蛋白酶 (MMP) 肽酶 M10 家族的成员。该家族中的蛋白质参与正常生理过程 (如胚胎发育、繁殖和组织重塑) 以及疾病过程 (如关节炎和转移) 中细胞外基质的分解。编码的前原蛋白经过蛋白水解处理以产生成熟的蛋白酶。这种分泌的蛋白酶分解纤连蛋白、层粘连蛋白、弹性蛋白、蛋白多糖核心蛋白、明胶和几种类型的胶原蛋白。该基因是 11 号染色体上 MMP 基因簇的一部分。[RefSeq 提供，2016 年 1 月]

This gene encodes a member of the peptidase M10 family of Matrix Metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

MMP10 基因产物(1)

mRNA	Protein	Name
NM_002425.3	NP_002416.1	stromelysin-2 preproprotein

MMP10 蛋白结构

PG_binding_1

Peptidase_M10

Hemopexin

0
100
200
300
400
476 a.a.

蛋白主名

其他名称

stromelysin-2

MMP-10	matrix metalloprotease 10
matrix metalloproteinase 10 (stromelysin 2)	matrix metalloproteinase-10
transin 2

重组 MMP10 蛋白

目录号	产品名	蛋白编号	纯度
HY-P700571	MMP-10 Protein, Human (P. pastoris, His)	P09238 (F99-C476)	≥95%

关联疾病

疾病名称

别名

Ophthalmomyiasis

Ocular Myiasis	Ophthalmic Myiasis
Myiasis Oestruosa

Middle Cerebral Artery Infarction

Infarction, Middle Cerebral Artery

Infarction Middle Cerebral Artery

Squamous Cell Carcinoma

Epidermoid Carcinoma	Squamous Cell Cancer
Carcinoma, Squamous Cell	Malignant Squamous Cell Tumor
Squamous Carcinoma	Squamous Cell Epithelioma
Squamous Cell Skin Cancer	Carcinoma Squamous Cell
Neoplasms, Squamous Cell	Squamous Cell Carcinoma - Category
Malignant Squamous Cell Neoplasm	Squamous Cell Carcinoma Of Skin

Skin Carcinoma

Skin Cancer	Carcinoma Of Skin
Ca - Skin Cancer	Cancer Of Skin
Malignant Neoplasm Of Skin	Melanoma And Non-Melanoma Skin Cancer
Skin Cancers	Cancer, Skin

Pyoderma Gangrenosum

Phagedenic Pyoderma

Phagedena Geometric

Arthritis

Inflammatory Joint Disease

Inflammatory Disorder Of Joint

Squamous Cell Carcinoma, Head And Neck

Squamous Cell Carcinoma Of The Head And Neck	HNSCC
Head And Neck Squamous Cell Carcinoma	Head And Neck Cancer
Squamous Cell Carcinoma Of Lip	Squamous Cell Carcinoma, Head And Neck, Somatic
Carcinoma Of The Head And Neck	Squamous Cell Carcinomas Of Head And Neck
Scchn	Squamous Cell Carcinoma Of The Hypopharynx
Squamous Cell Carcinoma Of The Oropharynx	Squamous Cell Carcinoma Of Salivary Glands
Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses	Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses
Squamous Cell Carcinoma Of The Oral Cavity	Squamous Cell Carcinoma Of The Lip
Carcinoma, Squamous Cell Of Head And Neck	Lip Squamous Cell Carcinoma
Cancer, Head/Neck	Carcinoma, Squamous Cell, Head And Neck
Salivary Gland Squamous Cell Carcinoma	Cancer Of Head And Neck
Squamous Cell Carcinoma Of Oropharynx Nos

Epidermolysis Bullosa Dystrophica

Dystrophic Epidermolysis Bullosa	Deb
Dermolytic Epidermolysis Bullosa	Epidermolysis Bullosa, Dermolytic
Epidermolysis Bullosa, Dystrophic	Epidermolysis Bullosa Dystrophic
Dystrophic Eb - [Epidermolysis Bullosa]

Pyoderma

Gingival Overgrowth

Gingival Enlargement	Gingival Hyperplasia
Gingival Bulge	Gingival Enlargement Nos
Gingival Hypertrophy	Gum Hypertrophy
Hyperplasia Gum	Gingival Thickening
Hyperplasia Of Gingiva	Hypertrophy Of Gingiva
Hypertrophy Of Mucous Membrane Of Gums

Keratoconus

Kc	Conical Cornea
Noninflammatory Corneal Thining	Bulging Cornea
Cornea Conical	Acquired Conus Of Cornea

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-P2185A	NFF-3 TFA	Chemical	98.57%	否
HY-161285	MMP-9/10-IN-2	Inhibitor	/	否
HY-P2185	NFF-3	Chemical	/	否
HY-RS08518	MMP10 Human Pre-designed siRNA Set A		/	否
HY-RS08519	Mmp10 Mouse Pre-designed siRNA Set A		/	否
HY-RS08520	Mmp10 Rat Pre-designed siRNA Set A		/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	MMP10	VGNC	VGNC:82014
Rattus norvegicus	MMP10	RGD	RGD:620192
Macaca mulatta	MMP10	VGNC	VGNC:74888
Mus musculus	MMP10	MGD	MGI:97007
Others	MMP10	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。沪(浦)应急管危经许[2021]201709(QFYS)

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MMP10 - matrix metallopeptidase 10 Gene

关于 MMP10

功能概要

MMP10 基因产物(1)

MMP10 蛋白结构

重组 MMP10 蛋白

关联疾病

直系同源

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MMP10 - matrix metallopeptidase 10 Gene

关于 MMP10

功能概要

MMP10 基因产物(1)

MMP10 蛋白结构

重组 MMP10 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z