1. Gene
  2. EPB41L4B - erythrocyte membrane protein band 4.1 like 4B Gene

EPB41L4B - erythrocyte membrane protein band 4.1 like 4B Gene

中文名称:红细胞膜蛋白带 4.1 样 4B

种属: Homo sapiens

同用名: CG1; EHM2; LULU2

基因 ID: 54566 | 基因类型: protein coding

关于 EPB41L4B

Cytogenetic location: 9q31.3 Genomic coordinates (GRCh38): 9:109,171,974-109,321,059 (from NCBI)

This gene has 2 transcripts (splice variants), 200 orthologues and 10 paralogues. Broad expression in colon (RPKM 20.8), thyroid (RPKM 15.3) and 18 other tissues.

功能概要

预计是细胞骨架的结构成分。参与多个过程,包括细胞粘附的正调节;角质形成细胞迁移的正向调节;和伤口愈合。在肌动球蛋白结构组织的上游或内部起作用。位于细胞顶端;胞质溶胶;和质膜。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be a structural constituent of Cytoskeleton. Involved in several processes, including positive regulation of cell adhesion; positive regulation of keratinocyte migration; and wound healing. Acts upstream of or within actomyosin structure organization. Located in apical part of cell; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EPB41L4B 基因产物(3)

mRNA Protein Name
NM_001385623.1 NP_001372552.1 band 4.1-like protein 4B isoform 3
NM_018424.3 NP_060894.2 band 4.1-like protein 4B isoform 1
NM_019114.5 NP_061987.3 band 4.1-like protein 4B isoform 2

EPB41L4B 蛋白结构

FERM_N

FERM_N: FERM N-terminal domain (89 - 165)

FERM_M

FERM_M: FERM central domain (169 - 277)

FERM_C

FERM_C: FERM C-terminal PH-like domain (283 - 370)

FA

FA: FERM adjacent (FA) (378 - 421)

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  • 900 a.a.
蛋白主名 其他名称

band 4.1-like protein 4B

FERM-containing protein CG1

直系同源

种属 基因名 来源 基因 ID
Bos taurus EPB41L4B VGNC VGNC:28524
Felis catus EPB41L4B VGNC VGNC:61896
Mus musculus EPB41L4B MGD MGI:1859149
Canis familiaris EPB41L4B VGNC VGNC:40397
Macaca mulatta EPB41L4B VGNC VGNC:103260
Rattus norvegicus EPB41L4B RGD RGD:1562988