2. Gene
  3. VSIR - V-set immunoregulatory receptor Gene

VSIR - V-set immunoregulatory receptor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：V 集免疫调节受体

种属: Homo sapiens

同用名: B7H5; GI24; B7-H5; Dies1; PD-1H; SISP1; VISTA; PP2135; C10orf54; DD1alpha

基因 ID: 64115 | 基因类型: protein coding

关于 VSIR

Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38): 10:71,747,556-71,773,520 (from NCBI)

This gene has 3 transcripts (splice variants), 482 orthologues and 14 paralogues. Broad expression in spleen (RPKM 39.2), bone marrow (RPKM 38.8) and 23 other tissues.

功能概要

启用内肽酶激活剂活性；酶结合活性；和相同的蛋白质结合活性。参与多个过程，包括细胞因子产生的负调节；大分子代谢过程的正向调控；和 T 细胞活化的调节。位于质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables endopeptidase activator activity; Enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of macromolecule metabolic process; and regulation of T cell activation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

VSIR 基因产物(1)

mRNA Protein Name
NM_022153.2 NP_071436.1 V-type immunoglobulin domain-containing suppressor of T-cell activation precursor

VSIR 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (43 - 150)

  • 0
  • 100
  • 200
  • 311 a.a.
蛋白主名 其他名称

V-type immunoglobulin domain-containing suppressor of T-cell activation

Death Domain1alpha

重组 VSIR 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7591 Recombinant Human VISTA/B7-H5/PD-1H Protein (CHO-expressed) Q9H7M9 /
HY-P70983 VISTA/B7-H5 Protein, Human (HEK293, His) AAH20568.1 (F33-A194) ≥95%
HY-P77879 VISTA/B7-H5 Protein, Human (HEK293, Fc) Q9H7M9 (F33-A194) ≥95%
HY-P78929 VISTA/B7-H5 Protein, Human (Biotinylated, HEK293, Fc-Avi) Q9H7M9 (F33-A194) ≥95%
HY-P78936 VISTA/B7-H5 Protein, Human (Biotinylated, HEK293, His-Avi) Q9H7M9 (F33-A194) ≥95%

关联疾病

疾病名称 别名
Hard Palate Cancer

Malignant Neoplasm Of Hard Palate

Malignant Tumor Of Hard Palate

Malignant Tumour Of Hard Palate
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15711 VSIR Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta VSIR VGNC VGNC:79834
Canis familiaris VSIR VGNC VGNC:51998
Bos taurus VSIR VGNC VGNC:50150
Rattus norvegicus VSIR RGD RGD:1590938
Felis catus VSIR VGNC VGNC:66980
Mus musculus VSIR MGD MGI:1921298
Others VSIR NCBI
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