2. Gene
  3. Bcl2l11 - Bcl2-like 11 Gene

Bcl2l11 - Bcl2-like 11 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：Bcl2 样11

种属: Rattus norvegicus

同用名: Bim; Bod; BimL

基因 ID: 64547 | 基因类型: protein coding

关于 Bcl2l11

Primary_assembly 3: 115,366,646-115,404,068 forward strand.mRatBN7.2:CM026976.1

This gene has 4 transcripts (splice variants), 116 orthologues, 2 paralogues and is associated with 4 phenotypes. Biased expression in Thymus (RPKM 6.4), Spleen (RPKM 47.5) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动动力蛋白复合物结合活性和蛋白激酶结合活性。预计有助于微管结合活动。参与多个过程，包括对淀粉样蛋白-β 的细胞反应；细胞对雌二醇刺激的反应；和响应 ER 超载的自噬的正调节。位于线粒体中。与人类 BCL2L11 同源（BCL2 like 11）。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable dynein complex binding activity and protein kinase binding activity. Predicted to contribute to microtubule binding activity. Involved in several processes, including cellular response to amyloid-beta; cellular response to estradiol stimulus; and positive regulation of Autophagy in response to ER overload. Located in mitochondrion. Orthologous to human BCL2L11 (BCL2 like 11). [provided by Alliance of Genome Resources, Apr 2022]

Bcl2l11 基因产物(1)

mRNA Protein Name
NM_171988.3 NP_741985.1 bcl-2-like protein 11

Bcl2l11 蛋白结构

Bim_N

Bim_N: pfam06773 (110 - 145)

Bclx_interact

Bclx_interact: pfam08945 (235 - 270)

  • 0
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  • 303 a.a.
蛋白主名 其他名称

bcl-2-like protein 11

BCL2-like 11 (apoptosis facilitator)

Bcl-2 related apoptotic gene product BimL

bcl-2-related ovarian death protein

bcl2-interacting mediator of cell death

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-153953 Bcl-2-IN-11 Inhibitor / 否
HY-RS01427 BCL2L11 Human Pre-designed siRNA Set A / 否
HY-RS01428 Bcl2l11 Mouse Pre-designed siRNA Set A / 否
HY-RS01429 Bcl2l11 Rat Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcl2l11 NCBI NCBI:10018
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