1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. Inlecitug

Inlecitug 是一种嵌合单克隆抗体,靶向人 KDR (激酶插入结构域受体)。Inlecitug 通过特异性结合 KDR,阻断血管内皮生长因子 (VEGF) 与 KDR 的结合,抑制血管生成,从而发挥抗肿瘤活性。Inlecitug 有望用于癌症的研究。

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CAS No. : 2997627-68-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Inlecitug is a chimeric monoclonal antibody targeting human KDR (kinase insert domain receptor). Inlecitug specifically binds to KDR, blocking the binding of vascular endothelial growth factor (VEGF) to KDR and inhibiting angiogenesis, thus exerting antitumor activity. Inlecitug is promising for research of cancers[1].

同型

Human IgG1 kappa

推荐同型对照抗体
反应种属

Human

IC50 & Target

KDR

基因 ID

3791  [NCBI]

Accession
应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • IgG1-kappa
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Inlecitug
目录号:
HY-P991141
需求量: