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  3. KRAS G12C inhibitor 14

KRAS G12C inhibitor 14 

目录号: HY-125872
产品使用指南

KRAS G12C inhibitor 14 是一种有效的 KRAS G12C 抑制剂,IC50 为 18 nM,详细信息请参考专利文献 WO2019110751A1 中的化合物 17。

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KRAS G12C inhibitor 14 Chemical Structure

KRAS G12C inhibitor 14 Chemical Structure

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Description

KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 17, has an IC50 of 18 nM[1].

IC50 & Target[1]

KRas G12C

18 nM (IC50)

Molecular Weight

484.88

Formula

C₂₄H₁₉ClF₂N₄O₃

SMILES

FC1=CC=CC(O)=[C@@]1[C@@]2=C(F)C(N=CC(N3C)=C4N5[C@H](CN(C(C=C)=O)CC5)C3=O)=C4C=C2Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
KRAS G12C inhibitor 14
目录号:
HY-125872
需求量:

KRAS G12C inhibitor 14

Cat. No.: HY-125872