2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Leptin (116-130)

Leptin (116-130) 是一种具有生物活性的瘦素片段。Leptin (116-130) 促进 AMPA 受体运输到突触并促进活动依赖性海马突触可塑性。Leptin (116-130) 在淀粉样蛋白毒性模型中防止海马突触破坏和神经元细胞死亡。Leptin (116-130) 具有研究阿尔茨海默病 (AD) 的潜力。

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Custom Peptide Synthesis

Leptin (116-130) Chemical Structure

Leptin (116-130) Chemical Structure

CAS No. : 189224-35-9

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Leptin (116-130) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Leptin (116-130) is a bioactive leptin fragment. Leptin (116-130) promotes AMPA receptor trafficking to synapses and facilitate activity-dependent hippocampal synaptic plasticity. Leptin (116-130) prevents hippocampal synaptic disruption and neuronal cell death in models of amyloid toxicity. Leptin (116-130) has the potential for the research of Alzheimer's disease (AD)[1].

分子量

1561.72

Formula

C₆₄H₁₀₈N₁₈O₂₅S
CAS 号
Sequence Shortening

SCSLPQTSGLQKPES
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Leptin (116-130) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Leptin (116-130)189224-35-9iGluRIonotropic glutamate receptorsleptin fragmentAMPAsynapsesynaptic plasticityhippocampalamyloid toxicityAlzheimer's diseaseInhibitorinhibitorinhibit

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