1. Metabolic Enzyme/Protease
  2. Cytochrome P450
  3. Licopyranocoumarin

Licopyranocoumarin  (Synonyms: 甘草吡喃香豆素)

目录号: HY-119804
产品使用指南

Licopyranocoumarin 是一种异黄酮,具有 CYP3A4 抑制活性,IC50 为 32 μM。Licopyranocoumarin 具有有效的神经保护活性。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Licopyranocoumarin Chemical Structure

Licopyranocoumarin Chemical Structure

CAS No. : 117038-80-9

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Licopyranocoumarin is an isoflavonoid that shows CYP3A4 inhibitory activity with an IC50 of 32 μM. Licopyranocoumarin has potent neuroprotective activities[1].

IC50 & Target[2]

CYP3A4

32 μM (IC50)

体外研究
(In Vitro)

Licopyranocoumarin(0.3-3 μM;48 小时)显着阻断 MPP+ 诱导的神经元 PC12D 细胞死亡和线粒体膜电位消失,这是由 JNK[1] 介导的。
Licopyranocoumarin(0.3-3 μM;36 小时)通过抑制活性氧 (ROS) 的生成来抑制 MPP+ 诱导的 JNK 活化,从而抑制 MPP+ 诱导的神经元 PC12D 细胞死亡[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: PC12D cell
Concentration: 0.3 μM, 1 μM, 3 μM
Incubation Time: 48 hours
Result: Inhibited MPP+-induced cell death.

Western Blot Analysis[1]

Cell Line: PC12D cell
Concentration: 0.3 μM, 1 μM, 3 μM
Incubation Time: 36 hours
Result: Attenuated JNK activity induced by MPP+.
分子量

384.38

Formula

C21H20O7

CAS 号
中文名称

甘草吡喃香豆素

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Licopyranocoumarin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Licopyranocoumarin
目录号:
HY-119804
需求量: