1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Lysophosphatidylcholine 18:2

Lysophosphatidylcholine 18:2 (Synonyms: 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC)

目录号: HY-N9410 纯度: ≥95.0%
产品使用指南

Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC),一种溶血磷脂,是一种从胰岛素抵抗 (IR) 多囊卵巢综合征 (PCOS) 中发现的潜在生物标志物。低血浆 Lysophosphatidylcholine 18:2 还可以预测糖耐量受损、胰岛素抵抗、2 型糖尿病、冠心病和记忆障碍。

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Lysophosphatidylcholine 18:2 Chemical Structure

Lysophosphatidylcholine 18:2 Chemical Structure

CAS No. : 22252-07-9

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Description

Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS). Low plasma Lysophosphatidylcholine 18:2 also has been shown to predict impaired glucose tolerance, insulin resistance, type 2 diabetes, coronary artery disease, and memory impairment[1][2].

IC50 & Target[1]

Human Endogenous Metabolite

 

In Vitro

Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC) contributes to the separation of IR PCOS and control groups. Significant decrease in the levels of phosphocholines (PCs) and lyso PC (18:2), and increase in trilauric glyceride level are observed in the plasma of IR PCOS[1].
Lysophosphatidylcholine (LPC), a major class of glycerophospholipids in human plasma, are implicated in inflammation, insulin resistance, obesity, and type 2 diabetes[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

519.65

Formula

C₂₆H₅₀NO₇P

CAS No.

22252-07-9

SMILES

CCCCC/C=C\C/C=C\CCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

References

Purity: ≥95.0%

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Keywords:

Lysophosphatidylcholine 18:21-Linoleoyl-2-Hydroxy-sn-glycero-3-PCEndogenous Metabolitelysophospholipidbiomarkerglucosetolerancetype2diabetesmemoryinsulinInhibitorinhibitorinhibit

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产品名称:
Lysophosphatidylcholine 18:2
目录号:
HY-N9410
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