2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. m-PEG11-Amine

m-PEG11-Amino 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联活性分子 (ADCs) 的合成。m-PEG11-Amine 也是一种基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。

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m-PEG11-Amine Chemical Structure

m-PEG11-Amine Chemical Structure

CAS No. : 854601-60-8

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规格 价格 是否有货 数量
100 mg ￥440
In-stock
250 mg ￥759
In-stock
500 mg ￥1259
In-stock
1 g ￥2050
In-stock
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10 g   询价  

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m-PEG11-Amine 相关抗体

Top Publications Citing Use of Products

查看 ADC Linker 亚型特异性产品:

查看所有亚型
Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

查看 PROTAC Linkers 亚型特异性产品:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG11-Amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

Cleavable Linker

 

PEGs

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

m-PEG11-Amine 相关抗体:
分子量

515.64

Formula

C23H49NO11
CAS 号
性状

固液混合物

颜色

Colorless to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

m-PEG11-Amine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

m-PEG11-Amine854601-60-8ADC LinkerPROTAC LinkersAntibody-drug conjugates linkercleavableADCantibody-drugconjugatesInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-W040222
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