1. Academic Validation
  2. Unguisins A and B: new cyclic peptides from the marine-derived fungus emericella unguis

Unguisins A and B: new cyclic peptides from the marine-derived fungus emericella unguis

  • J Nat Prod. 1999 May;62(5):787-9. doi: 10.1021/np980539z.
J Malmstrom 1
Affiliations

Affiliation

  • 1 Marine Chemistry Section, Department of Chemistry, University of Copenhagen, Denmark.
Abstract

Unguisin A (1) and B (2), the first cyclic heptapeptides containing GABA in the ring, were isolated from a marine-derived strain of Emericella unguis. The chemical structures of 1 and 2 were elucidated by extensive 2D NMR techniques, and the stereochemistry of the individual Amino acids was determined using Marfey's method.

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