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  3. Antibacterial and cytotoxic activity of the acetone extract of the flowers of Salvia sclarea and some natural products

Antibacterial and cytotoxic activity of the acetone extract of the flowers of Salvia sclarea and some natural products

  • Pak J Pharm Sci. 2007 Apr;20(2):146-8.
Edziri Hayet 1,  Bannour Fatma,  Ibrahim Souhir,  Fekih Abdel Waheb,  Kenani Abderaouf,  Aouni Mahjoub,  Mastouri Maha
Affiliations

Affiliation

  • 1 Laboratoire des substances biologiquement actives et des maladies transmissibles Faculté de Pharmacie-500-Monastir-Tunisia. hayetjaziri@yahoo.fr
PMID: 17416571
Abstract

The aim of this study was to investigate the Antibacterial and the cytotoxic activity of the acetone extract of the flowers of Salvia sclarea and of some Natural Products (sclareol, sclareolide and ambrox). The Antibacterial and the cytotoxic activity were determined by the dilution method. Sclareolide, ambrox and sclareol demonstrated a good Antibacterial activity against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27950, Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212. The acetonic extract of the flowers of Salvia sclarea has a significant cytotoxic activity against Hep-2 cells.

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