1. Academic Validation
  2. Triterpenoid saponins from Bellis bernardii

Triterpenoid saponins from Bellis bernardii

  • J Nat Prod. 1996 Oct;59(10):939-43. doi: 10.1021/np960400t.
T Schöpke 1 H Thiele K Hiller V Wray M Nimtz
Affiliations

Affiliation

  • 1 Humboldt-Universität zu Berlin, Institut für Pharmazie, Germany. schoepke@rz.uni-greifswald.de
Abstract

Nine saponins were isolated from the deacylated saponin mixture obtained from the whole Plants of Bellis bernardii. Their structures have been elucidated from NMR and MS data and by chemical derivatization. Three were glycosides of the recently reported bellisonic acid (2 beta, 3 beta,-23-trihydroxy-16-oxoolean-12-en-28-oic acid), with the major compounds being related glycosides of polygalacic acid (2 beta, 3 beta, 16 alpha, 23-tetrahydroxyolean-12-en-28-oic acid). In addition, a saponin of bayogenin (2 beta, 3 beta, 23-trihydroxyolean-12-en-28-oic acid) was obtained and is the first acyl glycoside of this aglycon with a free hydroxyl group at C-3.

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