2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Anti-infection
  3. RAR/RXR SARS-CoV
  4. MDI-403

MDI-403 是一种视黄酸受体 (RAR) 激动剂，其 EC50 < 1 μM。MDI-403 对 SARS-CoV-2 具有显著抗病毒活性，可剂量依赖性地抑制病毒核蛋白 (NP) 表达，降低感染细胞比例。MDI-403 主要作用于病毒入侵阶段。MDI-403 可用于抗 SARS-CoV-2 研究。

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MDI-403

MDI-403 Chemical Structure

CAS No. : 127471-94-7

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MDI-403 相关抗体

Top Publications Citing Use of Products

查看 RAR/RXR 亚型特异性产品:

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RXRα RXRβ RXRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MDI-403 is a retinoic acid receptor (RAR) agonist with an EC50 value of less than 1 μM. MDI-403 exhibits significant antiviral activity against SARS-CoV-2, and can dose-dependently inhibit the expression of viral nucleoprotein (NP) and reduce the proportion of infected cells. MDI-403 mainly acts during the virus invasion stage. MDI-403 can be used in research on anti-SARS-CoV-2[1].
分子量

448.59

Formula

C29H36O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MDI-403 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MDI-403127471-94-7MDI403MDI 403RAR/RXRSARS-CoVRetinoic acid receptorsRetinoid X receptorsSARS coronavirusSARS-CoV-2drug repurposingReFRAME libraryantiviral compoundsRAR agonisthigh-throughput screeningviral replication inhibitionVero E6 cellsdose-responsesynergy with remdesivirInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-W816575
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