2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. Nociceptin (1-13), amide

Nociceptin (1-13), amide 是一种有效的阿片受体 ORL1 (OP4) 受体激动剂，对小鼠输精管 pEC50 值为 7.9，与大鼠前脑膜结合的 Ki 值为 0.75 nM。

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Custom Peptide Synthesis

Nociceptin (1-13), amide Chemical Structure

Nociceptin (1-13), amide Chemical Structure

CAS No. : 178064-02-3

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Nociceptin (1-13), amide 的其他形式现货产品:

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Other Forms of Nociceptin (1-13), amide:

Nociceptin (1-13), amide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nociceptin (1-13), amide is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes[1][2].

IC50 & Target

Ki: 0.75 nM (binding to rat forebrain membranes)[1]
pEC50: 7.9 (in mouse vas deferens)[2]
体内研究
(In Vivo)

ORL1受体激动剂

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1381.59

Formula

C61H100N22O15
CAS 号
Sequence Shortening

FGGFTGARKSARK-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Nociceptin (1-13), amide 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nociceptin (1-13), amide178064-02-3Opioid ReceptorneuronschannelsautonomicnervoussystemfoodintakegastrointestinalmotilityInhibitorinhibitorinhibit

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