2. Metabolic Enzyme/Protease
  3. NADPH Oxidase
  4. NoxA1ds

NoxA1ds 是一种有效的和高选择性的 NADPH 氧化酶1 (NOX1) 抑制剂 (IC50=20 nM)。NoxA1ds 抑制 HT-29 人结肠癌细胞中 NOX1 衍生的 O2- 产生。NoxA1ds 在体外缺氧条件下减弱 VEGF 诱导的人肺动脉内皮细胞迁移。NoxA1ds 可用于高血压、动脉粥样硬化和肿瘤的研究。

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NoxA1ds

NoxA1ds Chemical Structure

CAS No. : 1435893-78-9

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规格 价格 是否有货 数量
1 mg ￥1200
In-stock
5 mg ￥3000
In-stock
10 mg ￥4800
In-stock
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Customer Review

Other Forms of NoxA1ds:

NoxA1ds 相关抗体

Top Publications Citing Use of Products

查看 NADPH Oxidase 亚型特异性产品:

查看所有亚型
NOX1 NOX2 NOX4 NOX5 DUOX1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NoxA1ds is a potent and highly selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM). NoxA1ds inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. NoxA1ds attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. NoxA1ds can be used in the study of hypertension, atherosclerosis and tumors[1].

IC50 & Target

NOX1

 

分子量

1125.32

Formula

C50H88N14O15
CAS 号
性状

固体

颜色

White to off-white

Sequence Shortening

EPVDALGKAKV-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

NoxA1ds 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NoxA1ds1435893-78-9NADPH OxidaseNOXefficaciousselectiveNox1-NOXA1hypertensionatherosclerosisneoplasiaInhibitorinhibitorinhibit

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