2. Metabolic Enzyme/Protease Anti-infection
  3. Cytochrome P450 Parasite
  4. Obtusifoliol

Obtusifoliol 是一种特异的 CYP51 抑制剂，Obtusifoliol 对布鲁氏锥虫 (TB) 和人 CYP51 的亲和力的 Kd 值分别为 1.2 µM 和 1.4 µM。

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Obtusifoliol Chemical Structure

Obtusifoliol Chemical Structure

CAS No. : 16910-32-0

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规格 价格 是否有货 数量
1 mg ￥3040
In-stock
5 mg ￥7600
In-stock
10 mg   询价  
50 mg   询价  

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Obtusifoliol 相关抗体

Top Publications Citing Use of Products

查看 Cytochrome P450 亚型特异性产品:

查看所有亚型
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

查看 Parasite 亚型特异性产品:

查看所有亚型
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Obtusifoliol is a specific CYP51 inhibitor, Obtusifoliol shows the affinity with Kd values of 1.2 µM and 1.4 µM for Trypanosoma brucei (TB) and human CYP51, respectively[1].

IC50 & Target

CYP51

 

Trypanosoma

 

体外研究
(In Vitro)

Obtusifoliol (0.1-100 µM; 48 hours) inhibit MCF-7 and MDA-MB231 breast cancer cells proliferation via arresting cell cycle progression and induction of apoptosis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Obtusifoliol 相关抗体:

Cell Viability Assay[2]

Cell Line: MCF-7; MDA-MB231 breast cancer cells
Concentration: 0.1, 1, 10, 40, 80, and 100 µM
Incubation Time: 48 hours
Result: Inhibited MCF-7 and MDA-MB231 breast cancer cells proliferation.
分子量

426.72

Formula

C30H50O
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: 99.86%

COA (194 KB) HNMR (119 KB) RP-HPLC (281 KB)

产品使用指南 (1538 KB)
参考文献

Obtusifoliol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Obtusifoliol16910-32-0Cytochrome P450ParasiteCYPsbreastcanerMCF-7MDA-MB231Inhibitorinhibitorinhibit

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目录号：
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