2. Odatroltide

Odatroltide  (Synonyms: DHDMIQK(KAP))

目录号: HY-132828
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Odatroltide 是一种纳米级 P-selectin 抑制剂，由 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid 和 KPAK 组成的靶向血栓的纳米给药体系。

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Odatroltide Chemical Structure

Odatroltide Chemical Structure

CAS No. : 1639303-73-3

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Odatroltide 相关抗体

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  • 生物活性

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生物活性

Odatroltide, as a nanoscale P-selectin inhibitor, is a nano-delivery system of 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to target the thrombus[1].

IC50 & Target

P-selectin[1]
体外研究
(In Vitro)

Odatroltide (1 nM) effectively down-regulates P-selectin expression. DHDMIQK(KAP) effectively inhibits platelet aggregation via down-regulating the expression of P-selectin. Odatroltide effectively inhibits platelet aggregations induced by TH, AA, ADP and PAF, which are correlated with the downregulation of P-selectin expression and with the scavenging of the free radicals[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Odatroltide 相关抗体:
体内研究
(In Vivo)

Odatroltide (0.01 nmol/kg) lyses the thrombus and inhibits thrombosis with a minimal[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

661.79

Formula

C32H51N7O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

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  • Do most proteins show cross-species activity?

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Keywords:

Odatroltide1639303-73-3DHDMIQK(KAP)nanoscalenano-deliveryfreeradicalsplateletaggregationsTHAAADPPAFInhibitorinhibitorinhibit

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