1. Others
  2. Others
  3. ORC-13661 hydrochloride

ORC-13661 hydrochloride 是一种毛细胞保护剂。ORC-13661 hydrochloride 保护感觉毛细胞免受氨基糖苷类和顺铂 (HY-17394) 的耳毒性。ORC-13661 hydrochloride 是一种可逆的机电传感器 (MET) 通道渗透阻滞剂。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

ORC-13661 hydrochloride Chemical Structure

ORC-13661 hydrochloride Chemical Structure

CAS No. : 1589571-77-6

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ORC-13661 hydrochloride is a hair cell protector. ORC-13661 hydrochloride protects sensory hair cells from aminoglycoside and Cisplatin (HY-17394) ototoxicity. ORC-13661 hydrochloride is a reversibly mechanoelectrical transducer (MET) channel permeant blocker[1].

体外研究
(In Vitro)

ORC-13661 (0.10-8.3 μM;野生型 *AB 斑马鱼毛细胞) hydrochloride 保护斑马鱼毛细胞免受多种氨基糖苷类 (AG) 的影响[1]
ORC-13661 (0.10-20 μM) hydrochloride 保护斑马鱼侧线毛细胞和哺乳动物毛细胞免受 Cisplatin (HY-17394) 影响[1]
ORC-13661 (0.3 and 3 μM) hydrochloride 是听觉毛细胞 MET 通道的可逆阻断剂。ORC-13661 hydrochloride 阻断 OHC MET 电流。ORC-13661 hydrochloride MET 通道块具有电压依赖性和渗透性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

ORC-13661 (0.2-5 mg/kg; 口服; 每日一次, 持续 10 天) hydrochloride 以剂量依赖性方式保护大鼠的听力免受阿米卡星的影响[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Fischer 344 rat[1]
Dosage: 0.2, 1, and 5 mg/kg
Administration: Oral administration; daily, for 10 days
Result: Protected hearing in mammals from different AG antibiotics.
分子量

427.35

Formula

C18H20Cl2N4O2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

ORC-13661 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
ORC-13661 hydrochloride
目录号:
HY-129677
需求量: