2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Parapenzolate bromide

Parapenzolate bromide，一种解痉挛剂，是一种具有口服活性的 mAChR 拮抗剂。Parapenzolate bromide 是一种抗胆碱能试剂。

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Parapenzolate bromide Chemical Structure

Parapenzolate bromide Chemical Structure

CAS No. : 5634-41-3

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Parapenzolate bromide 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Parapenzolate bromide, an antispasmodic, is an orally active mAChR antagonist. Parapenzolate bromide is an anticholinergic agent[1][2].

体内研究
(In Vivo)

Parapenzolate bromide (10 mg/kg, p.o. or i.v.) shows a significant analgesic effect in mice[1].
Parapenzolate bromide (0.5 mg/kg, i.v.) exhibits a spasmolytic activity in isolated gall bladder from guinea pigs[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice[1]
Dosage: 10 mg/kg
Administration: Oral administration (p.o.) or intravenous injection (i.v.)
Result: Prolonged the time until death in convulsive mice.
Animal Model: Guinea pigs[2]
Dosage: 0.5 mg/kg
Administration: Intravenous injection (i.v.)
Result: Antagonized contractions induced by acetylcholine (100 μg/kg, i.v.)
分子量

420.34

Formula

C21H26BrNO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Parapenzolate bromide 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Parapenzolate5634-41-3mAChRMuscarinic acetylcholine receptoranticholinergicsantispasmodiccontractionInhibitorinhibitorinhibit

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