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Pirepemat (IRL752) 是一种儿茶酚胺和认知促进剂。 Pireemat (IRL752) 可用于帕金森病的研究。

该游离形式化合物不稳定,推荐具有相同生物学活性的稳定盐形式 Pirepemat fumarate

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Pirepemat Chemical Structure

Pirepemat Chemical Structure

CAS No. : 1227638-29-0

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1 mg ¥1363
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5 mg ¥3000
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10 mg ¥4800
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25 mg ¥9500
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Pirepemat 的其他形式现货产品:

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Other Forms of Pirepemat:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson's disease[1][2].

体外研究
(In Vitro)

IRL752 displayed its highest in vitro affinities for 5-HT and NA-related targets[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

IRL752 (3.7-100 µmol/kg, s.c.) has no significant effect on acute hyper-dopaminergic or hypo-glutamatergic motor responses, but reversed deficits resulting from hypomonoaminergic function[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Normal rats[2].
Dosage: 3.7-100 µmol/kg.
Administration: s.c., 30 min prior to testing.
Result: Induced dose-dependent and regio-selective alterations in brain monoamine transmission indices and gene expression.
Clinical Trial
分子量

213.22

Formula

C11H13F2NO

CAS 号
性状

油状物

颜色

Off-white to brown

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Pirepemat 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Pirepemat
目录号:
HY-137447
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