1. PROTAC
  2. Ligand for E3 Ligase
  3. VH032 thiol

VH032 thiol (Synonyms: VHL ligand 6)

目录号: HY-111823 纯度: 95.91%
产品使用指南

VH032 thiol (VHL ligand 6) 是一种 von Hippel-Lindau 蛋白 (VHL) 配体。VH032 thiol (VHL ligand 6) 通过 linker 与 JQ1 结合从而形成 PROTAC 分子。

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VH032 thiol Chemical Structure

VH032 thiol Chemical Structure

CAS No. : 2098836-54-3

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Description

VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC[1].

IC50 & Target

VHL

 

Molecular Weight

490.64

Formula

C₂₃H₃₀N₄O₄S₂

CAS No.

2098836-54-3

SMILES

CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)S)NC(C)=O)=O)=O)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

VH032 thiolVHL ligand 6VHL ligand6VHL ligand-6Ligand for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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产品名称:
VH032 thiol
目录号:
HY-111823
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