1. Epigenetics TGF-beta/Smad
  2. PKC
  3. Psychosine

Psychosine  (Synonyms: Galactosylsphingosine)

目录号: HY-136490
COA 产品使用指南

Psychosine (Galactosylsphingosine) 是半乳糖脑苷脂酶 (GALC) 酶的底物,是 Krabbe 病的潜在生物标志物。Psychosine 是一种高度细胞毒性的脂质,能够在多种细胞类型中诱导细胞死亡,且有部分是通过细胞凋亡 (apoptosis) 导致的细胞死亡。Psychosine 还是一种 PKC 抑制剂。

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Psychosine Chemical Structure

Psychosine Chemical Structure

CAS No. : 2238-90-6

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1 mg ¥2247
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5 mg ¥5900
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Other Forms of Psychosine:

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Psychosine (Galactosylsphingosine), a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease[1]. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell types including, most relevantly to globoid cell leukodystrophy (GLD), oligodendrocytes. Psychosine causes cell death at least in part via apoptosis. Psychosine also is an inhibitor of PKC[1].

IC50 & Target[2]

PKC

 

体外研究
(In Vitro)

Psychosine 是 GALC 酶的底物,有望帮助诊断和随访通过新生儿筛查 (NBS) 确定的高危婴儿[1]。Psychosine 具有多效性,包括多种细胞通路的功能障碍[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[2]

Cell Line: Oligodendrocyte cells, M03.13
Concentration: 10, 20, and 40 μM
Incubation Time: 24 hours
Result: Caused cell death at least in part via apoptosis.
分子量

461.63

Formula

C24H47NO7

CAS 号
性状

固体

颜色

White to off-white

中文名称

鞘氨醇半乳糖苷;半乳糖基鞘氨醇

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

参考文献

Psychosine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HY-136490
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