2. Epigenetics TGF-beta/Smad Cell Cycle/DNA Damage Stem Cell/Wnt Cytoskeleton Metabolic Enzyme/Protease
  3. PKC ROCK Drug Metabolite
  4. (R)-AR-13503

(R)-AR-13503  (Synonyms: (R)-AR-13324 M1 metabolite)

目录号: HY-12798E 纯度: 98.20% ee.: 98.42%
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(R)-AR-13503 ((R)-AR-13324 M1 metabolite) 是 AR-13503 (HY-12798C) 的 (R)-对映体。AR-13503 是 AR-13324 甲磺酸盐的水解代谢物。AR-13324 是 ROCK 激酶和 PKC 抑制剂，具有抗血管生成和改善视网膜健康的作用，有望用于视网膜疾病研究。

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(R)-AR-13503 Chemical Structure

(R)-AR-13503 Chemical Structure

CAS No. : 2377238-62-3

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规格 价格 是否有货 数量
5 mg ￥3200
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10 mg ￥6000
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Other Forms of (R)-AR-13503:

(R)-AR-13503 相关抗体

Top Publications Citing Use of Products

查看 PKC 亚型特异性产品:

查看所有亚型
PKC PKCα PKCβ PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKC-ι ℩ PKCι

查看 ROCK 亚型特异性产品:

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ROCK ROCK1 ROCK2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(R)-AR-13503 ((R)-AR-13324 M1 metabolite) is the the (R)-enantiomer of AR-13503 (HY-12798C). AR-13503 is the hydrolytic metabolite of AR-13324 mesylate. AR-13324 is a ROCK kinase and PKC inhibitor with anti-angiogenic and retinal health-improving effects, showing potential for use in retinal disease research[1][2][3].

分子量

321.37

Formula

C19H19N3O2
CAS 号
性状

固体

颜色

Yellow to brown

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

(R)-AR-13503 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-AR-135032377238-62-3(R)-AR-13324 M1 metabolitePKCROCKDrug MetaboliteProtein kinase CRho-associated protein kinaseRho-associated kinaseRho-kinaseROKInhibitorinhibitorinhibit

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