ABCD3 蛋白, Human (Cell-Free, His)

ABCD3 is a member of the ATP-binding cassette (ABC) family. ABCD3 Protein, Human (Cell-Free, His) is the recombinant human-derived ABCD3 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of ABCD3 Protein, Human (Cell-Free, His) is 659 a.a., with molecular weight of 81.5 kDa.

ABCD3 是 ATP 结合盒 (ABC) 家族的成员，作为一种多功能 ATP 依赖性转运蛋白，具有广泛的底物特异性，促进各种代谢物的转运，包括长链脂肪酸 (LCFA)-CoA、二羧酸- CoA、长支链脂肪酸-CoA 和胆汁酸从细胞质到过氧化物酶体腔进行 β-氧化。该转运蛋白表现出脂肪酰辅酶A硫酯酶和ATP酶活性，可能有助于脂肪酰辅酶A在依赖ATP转运到过氧化物酶体之前水解成游离脂肪酸。ABCD3 在这些过程中的关键作用凸显了其在调节 LCFA 和能量代谢中的重要性，特别是在通过 β-氧化进行脂肪酸的降解和生物合成中。

Human

E. coli Cell-free

N-10*His

P28288 (M1-S659)

5825

MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS

81.5 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.