1. 重组蛋白
  2. CD Antigens
  3. T Cell CD Proteins B Cell CD Proteins Dendritic Cell CD Proteins Epithelial cell CD Proteins
  4. CD1d
  5. CD1D 蛋白, Human (HEK293, His)

CD1D 蛋白, Human (HEK293, His)

目录号: HY-P74327
产品使用指南

CD1D 蛋白是一种关键的抗原呈递分子,可结合自身和非自身糖脂,将它们呈递给自然杀伤 T 细胞上的 T 细胞受体。它与 B2M 合作,集中协调免疫反应,并且它与 MHC II 的相互作用强调了它在复杂的免疫系统调节网络中的重要性。CD1D 蛋白, Human (HEK293, His) 是重组的 CD1D 蛋白,由 HEK293 表达,带有 C-His 标签。CD1D 蛋白, Human (HEK293, His) 全长 301 个氨基酸,分子量为 45-50 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

The CD1D protein, a key antigen-presenting molecule, binds self and non-self glycolipids, presenting them to T-cell receptors on natural killer T-cells. Partnering with B2M, it centrally orchestrates immune responses, and its interactions with MHC II emphasize its significance in the intricate network of immune system regulation. CD1D Protein, Human (HEK293, His) is the recombinant human-derived CD1D protein, expressed by HEK293, with C-His labeled tag. The total length of CD1D Protein, Human (HEK293, His) is 301 a.a., with molecular weight of 45-50 kDa.

研究背景

CD1D-B2M 异二聚体蛋白是一种重要的抗原呈递分子,具有结合自身和非自身糖脂的独特能力,促进其呈递给自然杀伤 T 细胞上的 T 细胞受体。该蛋白质与 B2M(β-2-微球蛋白)形成异二聚体复合物,在协调免疫反应中发挥着核心作用。它与 MHC II 的相互作用进一步增强了它在复杂的免疫系统调节网络中的重要性。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

P15813 (M1-S301)

基因 ID

912  [NCBI]

蛋白结构
N-term
CD1D (M1-S301)
Accession # P15813
His
C-term
同用名
Antigen-presenting glycoprotein CD1d; CD1D; R3G1
分子量

45-50 kDa

纯度

Greater than 88% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD1D Protein, Human (HEK293, His)
目录号:
HY-P74327
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