2. 重组蛋白
  3. Cytokines and Growth Factors Immune Checkpoint Proteins CD Antigens
  4. TNF Superfamily Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins NK Cell CD Proteins Macrophage CD Proteins Stem Cell CD Proteins
  5. TNF Receptor Superfamily CD27
  6. CD27/NFRSF7 蛋白, Mouse (HEK293, mFc)

CD27/NFRSF7 蛋白, Mouse (HEK293, mFc)

目录号: HY-P78256
产品使用指南

CD27/NFRSF7 蛋白作为 CD70/CD27L 的受体，支持激活的 T 细胞存活，并可能通过与 SIVA1 相互作用影响细胞凋亡。它形成同二聚体并与 SIVA1 和 TRAF2 结合，表明在细胞过程中发挥不同的作用。CD27/NFRSF7 蛋白, Mouse (HEK293, mFc) 是重组的 CD27/NFRSF7 蛋白，由 HEK293 表达，带有 C-mFc 标签。CD27/NFRSF7 蛋白, Mouse (HEK293, mFc) 全长 159 个氨基酸，分子量为 60-70 kDa。

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3.  试用装只面向终端客户。

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描述

CD27/NFRSF7 Protein acts as a receptor for CD70/CD27L, supporting activated T-cell survival and potentially influencing apoptosis through interactions with SIVA1. It forms homodimers and engages with SIVA1 and TRAF2, indicating diverse roles in cellular processes. CD27/NFRSF7 Protein, Mouse (HEK293, mFc) is the recombinant mouse-derived CD27/NFRSF7 protein, expressed by HEK293, with C-mFc labeled tag. The total length of CD27/NFRSF7 Protein, Mouse (HEK293, mFc) is 159 a.a., with molecular weight of 60-70 kDa.
研究背景

CD27/NFRSF7 蛋白作为 CD70/CD27L 的受体，与活化 T 细胞的存活有关。此外，它可能通过与 SIVA1 相互作用在细胞凋亡中发挥作用。该蛋白形成同二聚体并与 SIVA1 和 TRAF2 结合，表明它参与多种细胞过程。
种属

Mouse
表达系统

HEK293
标签

C-mFc
蛋白编号

P41272 (P24-R182)
基因 ID

21940  [NCBI]
蛋白结构
N-term
CD27 (P24-R182)
Accession # P41272
mFc
C-term
同用名
CD27 antigen; Tp55; TNFRSF7; S152; T14; S152. LPFS2; MGC20393; S152CD27L receptor
分子量

60-70 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CD27/NFRSF7 Protein, Mouse (HEK293, mFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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