1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Stem Cell CD Proteins Epithelial cell CD Proteins Cell Adhesion Molecules (CAMs)
  4. CD66e/CEACAM5 Immunoglobulin-like Cell Adhesion Molecules
  5. Meconium Antigen 100/CEACAM5
  6. CEACAM5 蛋白, Cynomolgus (HEK293, His)

CEACAM5 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P76817
产品使用指南

CEACAM5蛋白是一种细胞表面糖蛋白,与癌胚抗原相关分子(如CEACAM6)配合参与细胞粘附、细胞内信号传导和肿瘤进展。CEACAM5 蛋白, Cynomolgus (HEK293, His) 是重组的 CEACAM5 蛋白,由 HEK293 表达,带有 C-His 标签。CEACAM5 蛋白, Cynomolgus (HEK293, His) 全长 688 个氨基酸,分子量为 105-140 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

CEACAM5 protein is a cell surface glycoprotein that cooperates with carcinoembryonic antigen-related molecules (such as CEACAM6) to participate in cell adhesion, intracellular signaling, and tumor progression. CEACAM5 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CEACAM5 protein, expressed by HEK293 , with C-His labeled tag. The total length of CEACAM5 Protein, Cynomolgus (HEK293, His) is 688 a.a., with molecular weight of 105-140 kDa.

研究背景

CEACAM5 蛋白是一种细胞表面糖蛋白,在细胞粘附、细胞内信号传导和肿瘤进展中发挥多方面的作用。CEACAM5 作为嗜同性和异嗜性细胞粘附的介质,与其他癌胚抗原相关细胞粘附分子(例如 CEACAM6)相互作用。在肿瘤进展的背景下,CEACAM5 作为癌基因,促进肿瘤进展并诱导结直肠癌细胞对失巢凋亡的抵抗力。此外,在微生物感染期间,CEACAM5 充当大肠杆菌 Dr 粘附素的受体,这些粘附素的结合导致 CEACAM5 同二聚体解离。这些不同的功能强调了 CEACAM5 在调节细胞过程中的多功能性,并强调了其在生理和病理环境中的重要性。

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

XP_005589491 (M1-A688)

基因 ID

102128791  [NCBI]

蛋白结构
N-term
CEACAM5 (M1-A688)
Accession # XP_005589491
His
C-term
同用名
Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e
分子量

105-140 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CEACAM5 Protein, Cynomolgus (HEK293, His)
目录号:
HY-P76817
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