Delta-like 蛋白 3/DLL3 蛋白, Human (HEK293, His-Avi)

Delta-like protein 3/DLL3 stands out as a pivotal regulator in neurogenesis and cellular differentiation. As an inhibitor of primary neurogenesis, DLL3 plays a crucial role in directing neurons along specific differentiation pathways. Its impact extends to somite boundary formation in the paraxial mesoderm segmentation. DLL3's ability to bind and activate Notch-1 or other Notch receptors highlights its significance in orchestrating cellular processes that govern developmental pathways and cellular fate determination. Delta-like protein 3/DLL3 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Delta-like protein 3/DLL3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Delta-like protein 3/DLL3 Protein, Human (HEK293, His-Avi) is 169 a.a., with molecular weight of 25-30 kDa.

Delta 样蛋白 3/DLL3 成为神经发生和细胞分化复杂过程中的关键调节因子。作为初级神经发生的抑制剂，DLL3被认为在引导神经元沿着特定分化途径发挥关键作用。它的参与超出了神经发生的范围，有助于轴旁中胚层分割过程中体节边界的形成。值得注意的是，DLL3 表现出结合和激活 Notch-1 或其他 Notch 受体的能力，强调了它在协调控制发育途径和细胞命运决定的细胞过程中的重要性。

Human

HEK293

C-Avi;C-His

Q9NYJ7-1 (V311-A479)

10683  [NCBI]

25-30 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.